RAD18 transmits DNA damage signalling to elicit homologous recombination repair
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منابع مشابه
RAD18 transmits DNA damage signalling to elicit homologous recombination repair
To maintain genome stability, cells respond to DNA damage by activating signalling pathways that govern cell-cycle checkpoints and initiate DNA repair. Cell-cycle checkpoint controls should connect with DNA repair processes, however, exactly how such coordination occurs in vivo is largely unknown. Here we describe a new role for the E3 ligase RAD18 as the integral component in translating the d...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2009
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb1865